Investigating the Changes in Venom-Specific IgE Induced by Wasp Venom Immunotherapy

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Investigating the Changes in Venom-Specific IgE Induced by Wasp Venom Immunotherapy

Patients with systemic reactions (SR) to Hymenoptera stings are successfully treated by venom immunotherapy (VIT), but there is not yet a general agreement on the criteria for stopping VIT. We discuss the importance of the venom-specific IgE levels among these criteria. In particular, the results from a recent study evaluating the IgE changes during a 5-year VIT, in patients stung and protected...

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Determinants of venom-specific IgE antibody concentration during long-term wasp venom immunotherapy

BACKGROUND Venom immunotherapy (VIT) is an effective treatment for subjects with systemic allergic reactions (SR) to Hymenoptera stings, however there are few studies concerning the relevance of the venom specific IgE changes to decide about VIT cessation. We assessed IgE changes during a 5-year VIT, in patients stung and protected within the first 3 years (SP 0-3) or in the last 2 years (SP 3-...

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Successful venom immunotherapy to paper wasp, in IgE-venom negative patient.

3. Maibach H.J., Johnson H.L. Contact urticaria syndrome. Contact urticaria to diethyltoluamide. Arch Dermatol 1975;111:726-730. 4. Miller JD. Anaphylaxis associated with insect repellent. N Engl J Med. 1982;307(21):1341—2. 5. Von Mayenburg J, Rakoski J. Contact urticaria to diethyltoluamide. Contact Dermatitis. 1983;9(2):171. 6. Vozmediano JM, Armario J, Gonzalez-Cabrerizo A. Immunologic conta...

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Wasp venom allergy: effect of anti-IgE antibody on wasp venom anaphylaxis in a mouse model.

BACKGROUND Although anti-IgE antibody (Ab) therapy was recently shown to be effective in patients with bronchial asthma, no study has reported the effect of IgE therapy in the prevention of wasp venom anaphylaxis. In this study, we used a mouse model of wasp venom allergy to investigate the effect of anti-IgE Ab on wasp venom anaphylaxis. METHODS We developed a mouse model of wasp venom aller...

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464 Specific Venom Ige Decrease during 5 Years of Venom Immunotherapy (VIT): Clinical Relevance in Stung and Not Stung Patients

deficiency and allergies. Methods: Clinical and laboratory tests were conducted on 579 potentially healthy people (172 women and 407 men, between 25 and 30 years), performed twice: in a diagnosis and after 6 to 12 months. Lymphocytes and NK cells from peripheral blood were assessed using cytometry. G, A, M immunoglobulin concentrations were determined by the turbidimetry. IgE concentration was ...

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ژورنال

عنوان ژورنال: Journal of Clinical & Cellular Immunology

سال: 2016

ISSN: 2155-9899

DOI: 10.4172/2155-9899.1000416